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10.30 a.m. Computational Systems Biology: A Tutorial P.S. Thiagarajan NUS, Singapore. 28-10-11 Abstract In Systems Biology, one studies the interactions between the components of biological systems, and how these interactions give rise to the functionality of the system. A common theme is to understand the dynamics of the biological process under study. Mathematical modeling and computational analysis play a vital role since typical processes will involve a large number of players and their complex interactions. Consequently computational systems biology, namely, the development of modeling and analysis techniques to aid the study of biological processes is a growing field which is attracting a variety of contributions from mathematicians, physicists, control theorists and computer scientists. Our goal is to survey this field from a computer science perspective. We will discuss stochastic and deterministic models and the accompanying analysis methods. We will also outline the main challenges facing the field. Time permitting, we will also sketch our work to date in this field. The tutorial will be approximately 90 minutes, with a short break midway.
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